Yulia Berry is an independent health researcher and author of the best selling e-books Aloe – Your Miracle Doctor and ‘Pharmacy in Vegetables’. She distributes a weekly newsletter regarding great home remedies and has written dozens of natural health articles published on hundreds of websites worldwide. Yulia Berry’s new ebook Unlocked Secrets of Curative Garlic to be released soon.
Archive for Cancer
Mar
02
Veeda Oncology is a vibrant Anglo/India CRO which brings together 20 years of clinical research expertise with the intellectual ability and tireless work ethic of the East. From First-in-Man studies to large scale Bioequivalence/Bioavailability comparator studies Veeda Clinical Research offers a fully integrated package to meet your early clinical development needs.
We provide phase 1 and phase II clinical trials and deliver cost effective research solutions for biotechnology oncology and pharmaceutical oncology. Veeda CR can take your compound from pre-clinical development to proof of concept in the most timely, cost effective manner.
Veeda Oncology is part of the Veeda Group that includes Veeda Clinical Research, which is a leading CRO specializing in the early clinical development of drugs with state of the art clinical pharmacology units in the UK, Europe and India, fully accredited GLP Laboratories and an established Biometrics team in Belgium and India.
Veeda Oncology is a global Oncology CRO with operations in India, Eastern Europe, Western Europe and the US. The company is a full service Oncology CRO for Phase I through Phase IV studies with the unique capability of providing rapid and strong global patient accrual with an effective cost structure.
Veeda Oncology is a full service CRO for Phase I through Phase IV studies with the unique capability of providing rapid and strong global patient accrual with an effective cost structure. Because of their geographic locations, the company is able to provide access to numerous clinical sites throughout the world resulting in greater access to patients with cancer and decreased time to study completion.
View our Oncology phase 1 trials,
Feb
10
Is the search for the cure for cancer more profitable than finding the cure?
Posted by: | CommentsIf you consider all the fund-raising and research development in search of cures, as well as the profits from current treatment regimes condoned by the FDA and cancer-experts, is it in the medical industry’s best interests to keep searching for the cure rather than actually find a cure for cancer?
And do you personally trust the pharmaceutical companies to provide the most effective form of treatment? Couldn’t they obtain more profits by marketing two less-effective treatments than one effective treatment?
Jan
04
Garlic, Cancer and You
Posted by: | CommentsGarlic – that oh so deliciously pungent bulb from the lily family that has been around humankind since the invention of writing, has been valued for its ability to spice up a meal, whet the appetite and to help cure a host of different ailments. Now, today’s researchers are taking a second look at garlic and are finding out that it not only helps makes things taste good, it might also play a role in preventing certain types of cancer.
Garlic and cancer
A number of studies have been done focusing on garlic’s organic allyl sulfur components and their ability to effectively inhibit the cancer process. These compounds make cells more vulnerable to the stress which is created when cells divide. Since cancer cells divide more rapidly than normal cells, they are susceptible to these specific stressors. Therefore, cancer cells have a much greater potential to suffer damage from the allyl sulfur compounds that are found in garlic.
The studies on garlic have revealed that garlic’s benefits are not limited to any specific species, to any particular tissue or even to a specific type of carcinogen. However, there is a strong link between garlic and the prevention on prostate and stomach cancers. 37 different observational studies have been done on people exploring the use of garlic and cancer prevention. Of the 37, 28 of the studies have revealed that garlic does play some role in cancer prevention.
It is important to note that these studies are observational: comparing the incidence of cancer among garlic and non-garlic consuming populations. Clinical studies are still needed for further verification, but unfortunately government funding for garlic research is limited and pharmaceutical companies are reluctant to study widely available plants that might have health benefits since there is no profit in it.
A complicated chemistry
Garlic’s chemistry is extremely complicated and how garlic products are manufactured and processed greatly effects the medicinal value of its various chemical constituents. Peeling garlic and then turning into an oil or powder can actually increase the number and variety of active compounds. The peeling process releases the enzyme allinase and kick starts the process that leads to the chemical reaction that produces diallyl disulfide. Diallyl Disulfide is also formed when garlic is crushed or chopped, however if it is cooked immediately after peeling and chopping the cancer fighting benefit of this sulfide is lost. Some secientis have recommended that you let the garlic sit for 15-20 minutes after it has been peeled in order to allow the allinase reaction to occur.
Dec
18
Revolutionizing Light Emitting Diodes : Bringing Relief In Cancer Clinical Trials
Posted by: | CommentsLight emitting diodes that were earlier associated as only an electronic light source, today has become a part of a noble cause – to help cure a person of cancer. This might sound a little abhorrent, but the truth is that the professors of neurology, pediatrics and hyper baric medicine at the Medical College of Wisconsin are convinced, that using LEDs can improve a bone-marrow transplant patient’s quality of life, after conducting several successful human trials.
This light emitting diode, an indispensable part of the optics and optical components, ensures a painless and secure process wherein an array of light helps ease or prevent some of the pain and discomfort associated with cancer treatment. This clinical trial is presently in its second part. As the first part was very encouraging, the doctors could not resist themselves from indulging in the expansion of these trials to several U.S. and foreign hospitals.
The scientists as well as the researchers are of the opine that the cells exposed to near infrared light from LEDs, grow 150 to 200 percent faster than cells not stimulated by such light. Thus, the healing process speeds up as the light arrays increase energy inside these cells. It came to notice that in the first trial, the use of LEDs showed a significant relief to pediatric bone-marrow transplant patients suffering the ravages of oral mucositis. Thus, LEDs were found to be effective in overcoming the common side effects of chemotherapy and radiation treatments. It was also found to be effective in the reduction of the mucositis problem which is very painful.
The treatment device that is creating this magic is the 3-by-5-inch portable, flat array of light-emitting diodes that is held on the outside of the patients cheek. However, a foil is placed between the flesh and the LED array to avoid any kind of sham treatment. This clinical trial will go on for about three more years to complete with a total of 80 patients.
After comparing the result of the first trial it was found that the percentage of patients with ulcerative oral mucositis to historical epidemiological controls were just 53 percent of the treated patients in the bone- marrow transplant group developed mucositis, considerably less than the usual rate of 70-90 percent. The researchers are still awaiting the the approval from the U.S. Food and Drug Administration, before the device can be made available for widespread use.
These Leds have proven to be of utmost importance in hundreds of applications. Among the optics and optical market, these light emitting diodes are also known to be beneficial in providing lights for plants that are grown on the Space Station as part of commercial experiments sponsored by NASA industry.
I am a product analyst for b2b industry. My core profile is to understand industry, develop information architecture and plan the product. Developed many B2b verticals. My core interest is research and analyse industry trends, latest updates in market, industry product information. Based on my experience i have studied harwdare product industry and my interest is to share that information and develop network for harwdare industry so that business manufaturers, suppliers, traders can benefit from this resource.
Dec
18
Revolutionizing Light Emitting Diodes : Bringing Relief In Cancer Clinical Trials
Posted by: | CommentsLight emitting diodes that were earlier associated as only an electronic light source, today has become a part of a noble cause – to help cure a person of cancer. This might sound a little abhorrent, but the truth is that the professors of neurology, pediatrics and hyper baric medicine at the Medical College of Wisconsin are convinced, that using LEDs can improve a bone-marrow transplant patient’s quality of life, after conducting several successful human trials.
This light emitting diode, an indispensable part of the optics and optical components, ensures a painless and secure process wherein an array of light helps ease or prevent some of the pain and discomfort associated with cancer treatment. This clinical trial is presently in its second part. As the first part was very encouraging, the doctors could not resist themselves from indulging in the expansion of these trials to several U.S. and foreign hospitals.
The scientists as well as the researchers are of the opine that the cells exposed to near infrared light from LEDs, grow 150 to 200 percent faster than cells not stimulated by such light. Thus, the healing process speeds up as the light arrays increase energy inside these cells. It came to notice that in the first trial, the use of LEDs showed a significant relief to pediatric bone-marrow transplant patients suffering the ravages of oral mucositis. Thus, LEDs were found to be effective in overcoming the common side effects of chemotherapy and radiation treatments. It was also found to be effective in the reduction of the mucositis problem which is very painful.
The treatment device that is creating this magic is the 3-by-5-inch portable, flat array of light-emitting diodes that is held on the outside of the patients cheek. However, a foil is placed between the flesh and the LED array to avoid any kind of sham treatment. This clinical trial will go on for about three more years to complete with a total of 80 patients.
After comparing the result of the first trial it was found that the percentage of patients with ulcerative oral mucositis to historical epidemiological controls were just 53 percent of the treated patients in the bone- marrow transplant group developed mucositis, considerably less than the usual rate of 70-90 percent. The researchers are still awaiting the the approval from the U.S. Food and Drug Administration, before the device can be made available for widespread use.
These Leds have proven to be of utmost importance in hundreds of applications. Among the optics and optical market, these light emitting diodes are also known to be beneficial in providing lights for plants that are grown on the Space Station as part of commercial experiments sponsored by NASA industry.
I am a product analyst for b2b industry. My core profile is to understand industry, develop information architecture and plan the product. Developed many B2b verticals. My core interest is research and analyse industry trends, latest updates in market, industry product information. Based on my experience i have studied harwdare product industry and my interest is to share that information and develop network for harwdare industry so that business manufaturers, suppliers, traders can benefit from this resource.
Dec
15
Terra med Alliance News: The drug Sprycel, approved for use by the U.S. Food and Drug Administration in patients with chronic myeloid leukemia, significantly inhibited the growth and invasiveness of ovarian cancer cells and also promoted their death, a study by researchers with UCLA’s Jonsson Comprehensive Cancer Center found.
Terra med Alliance News: The drug, when paired with a chemotherapy regimen, was even more effective in fighting ovarian cancer in cell lines in which signaling of the Src family kinases, associated with the deadly disease, is activated.
The study appears in the Nov. 10, 2009 edition of the British Medical Journal.
Ovarian cancer, which will strike 21,600 women this year and kill 15,500, causes more deaths than any other cancer of the female reproductive system. Few effective therapies for ovarian cancer exist, so it would be advantageous for patients if a new drug could be found that fights the cancer, said Gottfried Konecny, an assistant professor of hematology/oncology, a Jonsson Cancer Center researcher and first author of the study.
“I think Sprycel could be a potential additional drug for treating patients with Src dependent ovarian cancer,” Konecny said. “It is important to remember that this work is only on cancer cell lines, but it is significant enough that it should be used to justify clinical trials to confirm that women with this type of ovarian cancer could benefit.”
Recent gene expression studies have shown that about one-third of women have ovarian cancers with activated Src pathways, so the drug could potentially help 7,000 ovarian cancer patients every year.
In this study, the UCLA team tested the drug against 34 ovarian cancer cell lines and they conducted genetic analysis on all cell lines. Through these analyses, the researchers were able to identify genes that predict response to Sprycel. If the work is confirmed in human studies, it may be possible to test patients for Src activation and select those who would respond prior to treatment, personalizing their care.
“We were able to identify markers in the pre-clinical setting that would allow us to predict response to Sprycel,” Konecny said. “These may help us in future clinical trials in selecting patients for studies of the drug.”
Sprycel is what is known as a “dirty” kinase inhibitor, meaning it inhibits more than one pathway. Konecny said it also inhibits the focal adhesion kinase and ephrin receptor, also associated with ovarian cancer.
The next step, Konecny said, would be to test the drug on women with ovarian cancer in a clinical trial. The tissue of responders would then be analyzed to determine if the Src and other pathways were activated. If that is confirmed, it would further prove that Sprycel could be used to fight ovarian cancer. In studies, women would be screened before entering a trial and only those with Src dependent cancers could be enrolled to provide further evidence, Konecny said, much like the studies of the molecularly targeted breast cancer drug Herceptin enrolled only women who had HER-2 positive disease.
“Herceptin is different because we knew in advance that the only worked in women with HER-2 amplification,” he said. “In this case, we don’t clearly know that yet. The data reassure us that the drug works where the targets are over-expressed but we need more testing to confirm this.”
The tests combining the drug with chemotherapy are significant because chemotherapy currently is the first line treatment for ovarian cancer patients following surgery. Because Sprycel proved to have a synergistic effect when combined with chemotherapy — both made the other work better — it may be possible to add the targeted therapy as a first line treatment if its efficacy is confirmed in future studies, adding a new tool to an oncologist’s arsenal. Adapted from materials provided by University of California – Los Angeles, via EurekAlert!, a service of AAAS.
Terra med Alliance is a non-profit organization in the battle against leukemia helps children living with cancer and their families. Our goal is to make sure children battling cancer know they are not alone. For more information please visit www.terramedalliance.org. Email at contact@terramedalliance.org
Terra med Alliance is a non-profit organization in the battle against leukemia helps children living with cancer and their families. Our goal is to make sure children battling cancer know they are not alone. For more information please visit www.terramedalliance.org. Email at contact@terramedalliance.org
Nov
30
Dca for Cancer and the Side Effects of Dca
Posted by: | Comments
DCA, which is short for dichloroacetate acid, belongs to the family of chloroacetic acids. Coming from a methyl group, it has 3 hydrogen atoms of which 2 are replaced with chlorine atoms. This acidic chemical compound has salt properties, which are potassium dichloroacetate and sodium dichloroacetate, and these are known as dichloroacetates. These are being studied as potential cancer treatment. There has been much debate over the use of DCA for cancer since it is highly destructive and corrosive to the mucous membrane tissues and the respiratory tract.
Despite the fact that DCA cannot be patented, there are some individuals that have filed for a patent for cancer treatment purposes. The industry in pharmaceutics is not supporting the patent of DCA as a drug. There have been raised concerns that the lack of property protection from large and intellectual groups will lessen the economic incentive to gain the interest of pharmaceutical industry. In turn clinical studies and experiments of dichloroacetate acid may not receive proper funding. However, there are other existing funding sources from government organizations, like the FDA, and private charities. Because of the lack of funds, solicitations have been raised online. A total amount of more than $800,000 has been raised, which is adequate to finance the second phase of clinical study. This clinical experiment is used to apply for a drug patent to utilize DCA for cancer remedy or treatment.
An announcement in 2007 has been made claiming that dichloroacetate acid has been safely treated in patients for years. However, limited medical literature suggested that there have been side effects with the use of DCA. These include disturbances in the gait, numbness, and pain in a few patients. A previous clinical study involved the use of DCA to treat MELAS patients. This disease is one form of lactic acidosis, which is genetically inherited. The controlled treatment is 25 milligrams/kilogram/day. However, this was ended early on because it resulted in excessive toxicity in the peripheral nerve. DCA may also have sedative or anxiolytic side effects.
The studies that have been done on animal subjects suggested that the experienced neurotoxicity and neuropathy while on chronic treatment of DCA might be somewhat due to thiamine depletion. Since the rat subjects are supplemented with thiamine, these effects are lessened. Despite this discovery, current clinical studies revealed that there is still an occurrence of peripheral neuropathy during the chronic treatment of dichloroacetate acid, even if it has been co-administered with oral thiamine. Another experiment reported that the treatment of 50 milligram/kilogram/day of DCA have resulted to lethargy and unsteady gait in 2 patients. The first patient experienced the symptoms 1 month after the treatment, while the second patient experienced it after 2 months. Consciousness and steady gait are regained after stopping the administration. However, the potentials of sensory-nerve functions have not been recovered within 1 month.
While there are reports regarding the possible harm of dichloroacetate acid, there are still attempts to buffer down the acidity of the compound. There are several manufacturers that are coming up with their own DCA products. If you want to use DCA for cancer treatment, you can find a handful of websites that are selling the product. Not only are these online manufacturers supplying sodium dichloroacetate, they are also providing information regarding DCA. One of your online sources is Better DCA.
Better DCA is a huge supplier of pharmaceutical grade DCA for cancer . Their ninety-nine percent pure DCA is available to worldwide consumers.
Nov
28
Cancer Prevention Through Diet and Nutrition
Posted by: | Comments
In an attempt to keep anyone from wasting their time reading an article that does not apply to them we need to clearly define the subject of this article. If you are comfortable with waiting for a miracle drug to cure cancer, expecting that early detection through any number of exams at your physicians’ office followed by chemotherapy in an attempt to kill the now detectable cancer cells, then this article is not for you. If however, you would prefer to avoid cancer totally by preventing it before it starts, then please read on.
When addressing nutrition and the prevention of cancer one of the hottest topics in this arena at this time are antioxidants. The primary reason that antioxidants have received increasing attention is based on the very nature of cancer cells themselves, how they are started and more importantly how they can be eliminated before becoming detectable. For most forms of cancer, they get their start when your cell’s DNA becomes damage in some form. Keep in mind that your body is generating new cells on a daily basis and that these new cells are being created based on the blue print of how they should be constructed. That blue print is your DNA. When your DNA has become damaged or during the creation process of these new cells they come in contact with free radicals they are damaged. Unchecked that damage begins going through an uncontrolled growth and at some point this once damaged cells has now become a tumor.
While there is a lot of talk about antioxidants we really need to define what they are. Antioxidants are substances that protect cells from the damage caused by molecules known as free radicals. Antioxidants are capable of stabilizing free radicals and therefore prevent some of the damage free radicals otherwise might cause. Free radicals are unstable molecules caused by incomplete electron shells which make them more chemically reactive than those with complete electron shells. There are a number of environmental factors, including tobacco smoke, over exposure to the sun, pollution, toxins in our water, pesticides used in the growing of our vegetables and various other factors can also lead to free radical formation. The most common form of free radicals is oxygen – that’s correct the simple act of breathing that is required to keep us alive is the most common cause of free radical production in our bodies. When oxygen molecules become electrically charged or “radicalized” it tries to steal electrons from other molecules, causing damage to the DNA and other molecules. Over time, such damage may become irreversible and lead to various diseases including cancer. Antioxidants are often described as “mopping up” free radicals, meaning they neutralize the electrical charge and prevent the free radical from taking electrons from other molecules. Some examples of common antioxidants include beta-carotene, lycopene, vitamins C, E, and A, just to name a few. While not an antioxidant another very important mineral is Selenium, which is actually a component of antioxidant enzymes.
While diet and nutrition are beginning to get more attention we still have a long way to go, based on a number of statistics surrounding the average diet of more Americans. A simple search of American Journal of Clinical Nutrition will provide clinical research based on Diet, Nutrition and Cancer. While that may not be a big shock to you, you may be surprised to find that this particular entry has a copyright date from 1976. As a leading cause of death in the United States, one that is very preventable, one would expect to hear more about the impact of Diet, Nutrition and Exercise as it relates to the prevention of cancer. More often than not, if you pick up a newspaper or catch the news you are going to hear about the latest advances in chemotherapy, the newest drug for the treatment of cancer, the latest technology for improved mammograms and the list goes on. If you truly want to do something about the prevention of cancer you can’t wait on the news media and unfortunately not even your family physician to educate you on adopting a healthy lifestyle. Please don’t misunderstand that last comment as being a slam on doctors, because it is not. Every doctor that I know works extremely hard and puts in some very long hours.
Unfortunately, the way that our healthcare system is structured they do not get paid to educate you on a healthy lifestyle, nutrition, exercise or any of the things that you need to adopt as a comprehensive wellness program. The sad truth is that our healthcare system is setup to fix you after you’re broke, not to prevent you from getting to that point. It is truly up to YOU to take a proactive approach to learning what you need to know in order to adopt a overall healthy lifestyle/wellness program. It is important to note that a comprehensive wellness program leading to an overall healthy lifestyle is not something that you get to do for a week, a month or even just over the next year and then you’re done. This is a life long endeavor.
For those of you that are more of the do it yourself type people there are a large number of resources available to help you. From the internet to a staggering number of books that are published each year on the subject of healthy living, diet, nutrition, anti-aging. A very comprehensive guide to an overall healthy lifestyle that is very practical, pack with references to clinical research and an overall easy read is “The Metabolic Plan”, by Stephen Cherniske. The good news is that there is something for everyone. If you would prefer not to wade through mountains of information there are an increasing number of centers dedicated to Wellness, Healthy Lifestyles, and many of these facilities provide life coaches to help keep their clients accountable and on track. Even for the most dedicated person having an accountability partner of some type is a good idea to help during those stages of life where the motivation level just is not where it should be. Lastly, there are an increasing number of physicians that take a holistic approach to healing that includes a balanced approach which is one of the best approaches. In a perfect world our health would always be controllable through a balanced diet, good supplementation and exercise. However, the stark reality is that there are times that even our best efforts are not enough and we are forced to turn to a pharmaceutical to keep us in the game of life. In short all forms of healing have their place – there is not a one shoe fits all solution that will work for everyone, all the time.
Lastly, there are some well documented things that we can do to help prevent cancer.
- If you smoke – STOP
- Eating foods prepared with HIGH heat especially fried foods should be eliminated or reduced as much as possible.
- Increase the number of fruits and vegetables in your diet. Ideally 70% or more of your daily caloric intake should come from fruits and vegetables. If possible organically grown.
- Find a reputable supplements company grounded in science with products proven through strict clinical trials such as Univera LifeSciences. Even the best diet in the world is going to short on the vitamins, minerals and other nutrients that we need in a comprehensive wellness/anti-aging program.
- Exercise – We were built by our maker to move. Keep moving and stay active. Does the term use it or loose it mean anything to you? The American Cancer Society has a great section on their website titled “The Complete Guide to Nutrition and Physical Activity”
- Reduce your exposure to chemicals and toxins. Use biodegradable products when cleaning as they are much less harmful to you and the environment.
- Reduce the fat in your diets, but increase the essential fatty acids that are required by each of us – especially your brain and your joints.
- If you are overweight and/or obese reduce your weight as this is a very well documented cause of accelerated free-radical activity.
References:
1) Diet, nutrition, and cancer: American Journal of Clinical Nutrition, Vol 29, 1035-1047, Copyright © 1976 by The American Society for Clinical Nutrition, Inc, EN Alcantara and EW Speckmann
2) Nutrition and Cancer Prevention: New Insights into the Role of Phytochemicals: American Journal of Clinical Nutrition, Vol. 76, No. 1, 259, July 2002 © 2002 American Society for Clinical Nutrition
3) Nutrition and Activity Quiz: Are you living smart?: American Cancer Society
4) The Complete Guide- Nutrition and Physical Activity, American Cancer Society
5) Stephen Cherniske, M.S., The Metabolic Plan, The Random House Publishing Company, 2003, ISBN: 0-345-44102-8
Glenn has combined his passion for health and fitness with a great business model that allows him opportunities that would have otherwise not been possible. For more information visit http://www.opportunityofyourlife.com/
Nov
27
Clinical Trials of NON FDA approved Cancer therapies?
Posted by: | Comments
where in Europe and Canada can I find clinical trials of anticancer therapies? It seems people are finding non FDA approved drugs around the world that may help cure or slow down the cancer growth.
Nov
26
Now that CV247 has passed clinical trials on animals. Will it pass trials on humans?
Posted by: | CommentsI hope that they will pass. I don’t know about anyone else but i would sure jump at the chance to take the drug if i happened to get cancer. Seeing as it’s helped so many animals already, i would have to think twice about it.